Uncle Sam is, obviously, based on the same figure that appeared on the poster "I Want You For U.S Army". Uncle Sam is old yet muscular man with white hair and goatee. He's wearing white shirt with long-tailed jacket imprinted with white stars in blue color, red and white stripes pant, a white top hat with white star in blue line going around the hat, a shoulder guard with gold star and red bowtie. He wields pairs of two-barreled magnum guns and wears a belt with gun hostel on his right ride, which he stores his second magnum in. Apparently, his right hand is blue-colored with white stars on it and faded away when it reaches his wrist.
- Attack: Cataclysmal
- Life: Tank
- Speed: Slow
“When many thought that he was but a symbol of a long-gone past, he has returned, and is now ready to fight and defend the honour of an entire nation! More real than ever, he will teach his opponents the true meaning of his motto - "I want you to die!"
- He is so far the most expensive nonupgradeable(by Stars) mutant ever released to the Shop - it costs 3,500.
- The "I want you to die" second attack is a parody of his "I want you for U.S Army" poster.