Neo-Urban XIII is an Exclusive Cyber-Necro mutant. It can only be obtained by collecting all the mutants in the Big Boss! Reactor or collecting all of the mutants in the Saber column of the Legendary Mutants Bingo grid.
Appears to be Baron Urban, his clone has undergone a mutation which has made his body viscous enough for him to bond with a gigantic robotic suit.
- Attack: Apocalyptical
- Life: Tank
- Speed: Very Slow
“The relationship between Eva and Urban has always been a mix of attraction and hatred. This creature illustrates exactly that. For years, Baron Urban has engaged in self-cloning experiments to create a perfect body for himself. The first clones died quickly, destroying parts of Urban's lab with their fury. The XIIIth was a failure too, but it survived. Its only motivation is to find Eva and absorb her. In the meantime, it destroys indistinctly every Mutant in its way."
- When released, this mutant had the highest attack stat in the game.
- This mutant is the first Reactor Exclusive mutant to be obtainable in two different ways.
- This mutant may have been inspired by Clayface from the Batman cartoon.
- This mutant is also the largest in the game.